HMB - Beta-hydroxy beta-methylbutyrate 

Minimize protein breakdown! 

Maximizing Muscle Gains! 

 

Bill Philips first brought HMB or beta-hydroxy beta-methylbutyrate to the attention of bodybuilders back in the early to mid 1990’s. Since then, it has received widespread promotion in bodybuilding magazines and books, hundreds of newspapers, and it's even been featured on dozens of TV news programs. It’s been called everything from an exciting, breakthrough supplement, for maximizing muscle gains, to a total scam! 

 

Unlike most bodybuilding supplements that have poor scientific basis but volumes of positive anecdotal reports, HMB is just the opposite; the scientific evidence seems promising but bodybuilders don’t seem to be overly enthused about it’s effects on muscle gains or it’s reported ability to minimize protein breakdown.   

 

Background 

HMB is a metabolite of the branched-chain amino acid leucine. It is found in both plant and animal foods, and is also produced naturally in the body. Most individuals can manufacture .3 grams to 1 gram of HMB per day. Its precursors are the amino acid leucine and the keto acid KIC. While found in high concentrations in such foods as grapefruit and some species of fish, it is extremely difficult and impractical to consume enough of these foods on a daily basis to provide the full benefits of HMB. It probably makes more sense to take it in supplement form. 

 

What it does
Even the most die-hard of HMB supporters will admit that they are not exactly sure HMB works in the body. The prevailing theory is that it enhances the body's ability to minimize protein breakdown (called catabolism) in response to various forms of stress including intense exercise. By minimizing such catabolic reactions, HMB (when combined with a resistance-training program), may promote an increase in muscle gains and strength.  

 

The research  

Sports’ nutritionists and researchers have extensively studied HMB. Numerous species of animals including humans have been studied while using HMB. To date the safety and effectiveness of the compound suggests that HMB is both safe and potential valuable as an athletic aid for humans. For example in one study, test subjects who used three grams of HMB a day gained more lean mass and experienced greater strength and muscle gains, in just three weeks, than those who did not use the product.  

 

HMB side effects
Given that humans naturally produce an average of .3 to 1 gram of HMB per day, and that it occurs naturally in such foods as grapefruit and fish, it’s not surprising that no side effects have been reported. The long-term side effects are unknown at this point as HMB supplements have only been available since the mid 1990’s.  

 

How to use HMB
To minimize protein breakdown and maximize muscle gains, HMB is one of the simplest supplements to use. The recommended dosage is 3 to 5 grams per day. Most bodybuilders simply add it to their protein shake or sprinkle it on regular food.